The preparation of pharmaceutical water should comply with the requirements of quality management standards for pharmaceutical production from water treatment systems design, material selection, preparation process, storage, distribution and use. The water production system should be verified, and a routine monitoring, testing and reporting system should be established, and there should be complete original records for future reference. The pharmaceutical water system should be regularly cleaned and disinfected, and disinfection can be performed by heat treatment or chemical treatment. The disinfection method used and the removal of the disinfectant after chemical treatment should be validated.
The process of preparation and purification in the pharmaceutical industry is roughly divided into the following categories:
1. Raw water → raw water pressure pump → quartz sand filter → activated carbon filter → water softener (optional) → security filter → primary reverse osmosis equipment → sterile pure water tank → pure water booster pump → ultraviolet sterilizer →Microporous filter→EDI system→sterile purified water tank→ozone sterilizer→purified water booster pump→ozone sterilizer→ultraviolet sterilizer→microporous filter→water point
2. Raw water → raw water pressure pump → quartz sand filter → activated carbon filter → water softener (optional) → security filter → first-stage reverse osmosis → pure water tank → pure water booster pump → second-stage reverse osmosis → sterile purified water tank → ozone sterilizer → purified water booster pump → ozone sterilizer → ultraviolet sterilizer → microporous filter → water point
3. Raw water → raw water pressure pump → quartz sand filter → activated carbon filter → water softener (optional) → security filter → first-stage reverse osmosis machine → pure water tank → pure water booster pump → second-stage reverse Penetration→sterile pure water tank→pure water booster pump→ultraviolet sterilizer→microporous filter→EDI system→bacteria purified water tank→ozone sterilizer→purified water booster pump→ozone sterilizer→ultraviolet sterilizer→micropore Filter → water point (this process is recommended for the conductivity of raw water above 1000μS)